RMI1 Antibody

Size

100ug

Clone Number

Aliases

BLAP75 antibody; BLM associated polypeptide 75 kDa antibody; BLM associated protein 75 kDa antibody; BLM-associated protein of 75 kDa antibody; C9orf76 antibody; FAAP75 antibody; FLJ12888 antibody; Homolog of yeast RecQ mediated genome instability 1 antibody; RecQ mediated genome instability 1 antibody; RecQ-mediated genome instability protein 1 antibody; Rmi1 antibody; RMI1 homolog antibody; RMI1 RecQ mediated genome instability 1 homolog antibody; RMI1_HUMAN antibody; RP11-346I8 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9H9A7

Immunogen

Recombinant Human RecQ-mediated genome instability protein 1 protein (181-443AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background

Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RMI1

Research Areas

Epigenetics and Nuclear Signaling