RIP3(Phospho-Ser227) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases| and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm| and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex| and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phosho peptide around human RIP3 (Ser227)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

RIP3 ;Ser227 ; Receptor-interacting serine/threonine-protein kinase 3; EC 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3