Ribosomal Protein S6 Polyclonal Antibody

Ab type

Primary antibody

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS6 encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. 40S ribosomal protein S6 belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human S6 Ribosomal Protein. AA range:191-240

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

28681

synonyms

RPS6; OK/SW-cl.2; 40S ribosomal protein S6; Phosphoprotein NP33