RHOB Antibody, Biotin conjugated

Size

100ul

Clone Number

Aliases

Aplysia RAS-related homolog 6 antibody; ARH6 antibody; ARHB antibody; H6 antibody; MST081 antibody; MSTP081 antibody; oncogene RHO H6 antibody; ras homolog family member B antibody; ras homolog gene family; member B antibody; Rho cDNA clone 6 antibody; Rho related GTP binding protein RhoB Precursor antibody; Rho-related GTP-binding protein RhoB antibody; Rhob antibody; RHOB_HUMAN antibody; RHOH6 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P62745

Immunogen

Recombinant Human Rho-related GTP-binding protein RhoB protein (1-196AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RHOB

Research Areas

Signal transduction