RhoA(Phospho Ser188) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the Rho family of small GTPases| which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape| attachment| and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human RhoA (Phospho Ser188)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

21230

synonyms

RhoA ;Phospho Ser188; Transforming protein RhoA; Rho cDNA clone 12; h12