RHG24 Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human protein . at AA range: 550-630

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Rho GTPase-activating protein 24 ;Filamin-A-associated RhoGAP;FilGAP;RAC1- and CDC42-specific GTPase-activating protein of 72 kDa;RC-GAP72;Rho-type GTPase-activating protein 24;RhoGAP of 73