RGS20 Antibody

Size

100ul

Clone Number

Aliases

G(z)GAP antibody; Gz selective GTPase activating protein antibody; Gz-GAP antibody; Gz-selective GTPase-activating protein antibody; HGNC:14600 antibody; Regulator of G protein signaling 20 antibody; Regulator of G-protein signaling 20 antibody; Regulator of G-protein signaling Z1 antibody; Regulator of Gz selective protein signaling 1 antibody; Regulator of Gz-selective protein signaling 1 antibody; RGS20 antibody; RGS20_HUMAN antibody; RGSZ1 antibody; ZGAP1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O76081

Immunogen

Recombinant Human Regulator of G-protein signaling 20 protein (1-241AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200, IF:1:50-1:200

Background

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RGS20

Research Areas

Signal transduction