RGS1 Antibody

Size

100ug

Clone Number

Aliases

1R20 antibody; B cell activation protein BL34 antibody; B-cell activation protein BL34 antibody; BL34 antibody; Early response protein 1R20 antibody; IER 1 antibody; IER1 antibody; Immediate early response 1 B cell specific antibody; immediate-early response 1, B-cell specific antibody; IR20 antibody; Regulator of G protein signalling 1 antibody; Regulator of G-protein signaling 1 antibody; RGS 1 antibody; RGS1 antibody; RGS1_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q08116

Immunogen

Recombinant Human Regulator of G-protein signaling 1 protein (14-209AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894). Inhibits B cell chemotaxis toward CXCL12 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RGS1

Research Areas

Signal transduction