RFX2 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

DNA-binding protein RFX2 antibody; HLA class II regulatory factor RFX2 antibody; regulatory factor X 2 (influences HLA class II expression) antibody; Regulatory factor X 2 antibody; regulatory factor X2 antibody; RFX2 antibody; RFX2_HUMAN antibody; trans acting regulatory factor 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P48378

Immunogen

Recombinant Human DNA-binding protein RFX2 protein (1-130AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Transcription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (By similarity). Recognizes and binds the X-box, a regulatory motif with DNA sequence 5\'-GTNRCC(0-3N)RGYAAC-3\' present on promoters (PubMed:10330134). Probably activates transcription of the testis-specific histone gene HIST1H1T (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RFX2

Research Areas

Epigenetics and Nuclear Signaling