RELT Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by RELT (RELT tumor necrosis factor receptor) is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of RELT encoding the same protein have been reported.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human RELT. AA range:381-430

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

46092

synonyms

RELT; TNFRSF19L; Tumor necrosis factor receptor superfamily member 19L; Receptor expressed in lymphoid tissues