Recombinant Klotho (KL)

Core Catalog No.

H757Ra

Sequence

Leu517~Leu956

Predicted Molecular Mass(KD)

55kDa

Accurate Molecular Mass(KD)

55kDa

Purity

> 95%

Uniprot Link

Q9Z2Y9

Subcellular location

Membrane, Secreted

Isoelectric Point

6.4

Item Name

Klotho

Alternative Names

KLa; Klotho Alpha

Buffer

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Traits

Freeze-dried powder

Research Area

Metabolic pathway,

Citation

抗衰老蛋白Klotho 阻断高糖培养的大鼠肾小球系膜细胞TLR4/NF-κB p65/NGAL 通路的激活及其作用机制;The function of miR-199a-5p/Klotho regulating TLR4/NF-κB p65/NGAL pathways in rat mesangial cells cultured with high glucose and the mechanism;Klotho Inhibits Proliferation and Migration of Angiotensin II-Induced Vascular Smooth Muscle Cells (VSMCs) by Modulating NF-κB p65, Akt, and Extracellular Signal …;

Expression System

Prokaryotic expression

Source (Host)

E.coli

Organism species

Rattus norvegicus (Rat)

Appilcaiton

Positive Control; Immunogen; SDS-PAGE; WB.