REC8 Antibody

Size

100ul

Clone Number

Aliases

Cohesin Rec8p antibody; Human homolog of rad21 S. pombe antibody; Meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family antibody; Meiotic recombination protein REC8 homolog antibody; Meiotic recombination protein REC8-like 1 antibody; rec8 antibody; REC8 homolog (yeast) antibody; REC8 like 1 antibody; REC8_HUMAN antibody; Rec8p antibody; Recombination and sister chromatid cohesion protein homolog antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95072

Immunogen

Recombinant Human Meiotic recombination protein REC8 homolog protein (1-270AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

REC8

Research Areas

Epigenetics and Nuclear Signaling; Cell biology