RDH12 Antibody

Size

100ul

Clone Number

Aliases

All trans and 9 cis retinol dehydrogenase antibody; All-trans and 9-cis retinol dehydrogenase antibody; LCA 3 antibody; LCA13 antibody; LCA3 antibody; RDH 12 antibody; RDH12 antibody; RDH12_HUMAN antibody; Retinol dehydrogenase 12 (all trans/9 cis/11 cis) antibody; Retinol dehydrogenase 12 all trans and 9 cis antibody; Retinol dehydrogenase 12 antibody; RP53 antibody; SDR7C2 antibody; Short chain dehydrogenase/reductase family 7C member 2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96NR8

Immunogen

Recombinant Human Retinol dehydrogenase 12 protein (182-316AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RDH12

Research Areas

Neuroscience; Cancer; Metabolism; Signal transduction