RBM17 Antibody

Size

100ul

Clone Number

Aliases

45 kDa-splicing factor antibody; RBM 17 antibody; Rbm17 antibody; RNA binding motif protein 17 antibody; RNA-binding motif protein 17 antibody; SPF 45 antibody; SPF45 antibody; SPF45_HUMAN antibody; Splicing factor (45 kD) antibody; Splicing factor (45kD) antibody; Splicing factor 45 antibody; Splicing factor 45 kDa antibody; Splicing factor 45kDa antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96I25

Immunogen

Recombinant Human Splicing factor 45 protein (1-240AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Splice factor that binds to the single-stranded 3\\\'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RBM17

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience