RBBP5 Antibody

Size

100ul

Clone Number

Aliases

RBBP 5 antibody; RBBP-5 antibody; RBBP5 antibody; RBBP5_HUMAN antibody; RBQ 3 antibody; RBQ3 antibody; Retinoblastoma binding protein 5 antibody; Retinoblastoma binding protein RBQ3 antibody; Retinoblastoma binding protein5 antibody; Retinoblastoma-binding protein 5 antibody; Retinoblastoma-binding protein RBQ-3 antibody; SWD1 antibody; SWD1; Set1c WD40 repeat protein; homolog antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15291

Immunogen

Recombinant Human Retinoblastoma-binding protein 5 protein (319-538AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 \\\'Lys-4\\\' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at \\\'Lys-4\\\' of histone H3. Histone H3 \\\'Lys-4\\\' methylation represents a specific tag for epigenetic transcriptional activation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RBBP5

Research Areas

Epigenetics and Nuclear Signaling; Cancer