RASSF7 Antibody

Size

100ug

Clone Number

Aliases

C11orf13 antibody; Chromosome 11 open reading frame 13 antibody; HRAS1 antibody; HRAS1 related cluster 1 antibody; HRAS1 related cluster protein 1 antibody; HRAS1-related cluster protein 1 antibody; HRC1 antibody; MGC126069 antibody; MGC126070 antibody; Ras association (RalGDS/AF 6) domain family (N terminal) member 7 antibody; Ras association (RalGDS/AF 6) domain family 7 antibody; Ras association domain containing protein 7 antibody; Ras association domain-containing protein 7 antibody; RASF7_HUMAN antibody; RASSF 7 antibody; RASSF7 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q02833

Immunogen

Recombinant Human Ras association domain-containing protein 7 protein (300-368AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background

Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RASSF7

Research Areas

Epigenetics and Nuclear Signaling; Cell biology; Tags & Cell Markers