RASSF5 Antibody

Size

100ul

Clone Number

Aliases

Maxp 1 antibody; MAXP1 antibody; MGC10823 antibody; MGC17344 antibody; New ras effector 1 antibody; NORE 1 antibody; NORE1 antibody; NORE1A antibody; NORE1B antibody; Novel Ras effector 1 antibody; RAP1 Binding Protein antibody; RAPL antibody; Ras association (RalGDS/AF 6) domain family 5 antibody; Ras association (RalGDS/AF 6) domain family member 5 antibody; Ras association domain containing family protein 5 antibody; Ras association domain-containing protein 5 antibody; Ras effector like protein antibody; RASF5_HUMAN antibody; RASSF 3 antibody; RASSF 5 antibody; RASSF3 antibody; RASSF5 antibody; Regulator for cell adhesion and polarization enriched in lymphoid tissue antibody; Regulator for cell adhesion and polarization enriched in lymphoid tissues antibody; Tumor suppressor RASSF3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8WWW0

Immunogen

Recombinant Human Ras association domain-containing protein 5 protein (1-265AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RASSF5

Research Areas

Cancer; Cell biology; Signal transduction