RALBP1 Antibody

Size

100ug

Clone Number

Aliases

RLIP1 antibody; 76 kDa Ral-interacting protein antibody; 76-kDa Ral-interacting protein antibody; Dinitrophenyl S-glutathione ATPase antibody; DNP-SG ATPase antibody; Ral-interacting protein 1 antibody; Ral-interacting protein 1, 76-KD antibody; RalA-binding protein 1 antibody; RalBP1 antibody; RBP1_HUMAN antibody; RIP1 antibody; RLIP1 antibody; RLIP76 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q15311

Immunogen

Recombinant Human RalA-binding protein 1 protein (6-105AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RALBP1

Research Areas

Cell biology; Immunology; Signal transduction