RAD18 Antibody

Size

100ug

Clone Number

Aliases

2810024C04Rik antibody; DNA repair protein rad18 antibody; E3 ubiquitin-protein ligase RAD18 antibody; EC 6.3.2.- antibody; hHR 18 antibody; hHR18 antibody; hRAD 18 antibody; hRAD18 antibody; MGC156682 antibody; Postreplication repair E3 ubiquitin-protein ligase RAD18 antibody; Postreplication repair protein hRAD18p antibody; Postreplication repair protein RAD18 antibody; RAD 18 antibody; RAD18 antibody; RAD18 homolog (S. cerevisiae) antibody; RAD18 homolog antibody; RAD18 S. cerevisiae homolog antibody; RAD18 S. cerevisiae homolog of antibody; RAD18 transcript variant antibody; RAD18_HUMAN antibody; Rad18sc antibody; Radiation sensitivity protein 18 antibody; RING finger protein 73 antibody; RNF 73 antibody; RNF73 antibody; Structural maintenance of chromosomes protein 6 antibody; YCR066W antibody; YCR66W antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NS91

Immunogen

Recombinant Human E3 ubiquitin-protein ligase RAD18 protein (1-495AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on Lys-164. Has ssDNA binding activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RAD18

Research Areas

Epigenetics and Nuclear Signaling; Cell biology