RAC3 Antibody

Size

100ul

Clone Number

Aliases

OTTMUSP00000004488 antibody; p21 Rac3 antibody; p21-Rac3 antibody; Rac1B antibody; RAC3 antibody; RAC3_HUMAN antibody; RAS related C3 botulinum substrate 3 antibody; Ras related C3 botulinum toxin substrate 3 (rho family small GTP binding protein Rac3) antibody; Ras related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac3) antibody; Ras-related C3 botulinum toxin substrate 3 antibody; Rho family small GTP binding protein Rac3 antibody; RP23-84C12.18 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P60763

Immunogen

Recombinant Human Ras-related C3 botulinum toxin substrate 3 protein (1-192AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RAC3

Research Areas

Cancer; Signal transduction