ABCbiolab
SKU:ABCB04730
Rac GAP1 Polyclonal Antibody
Rac GAP1 Polyclonal Antibody
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Ab type
Primary antibody
Background
RACGAP1 encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. Rac GTPase activating protein 1 binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. Rac GTPase activating protein 1 plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for RACGAP1. There is a pseudogene for RACGAP1 on chromosome 12.
Reactivity
Human;Mouse;Rat;Monkey
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human GTPase Activating Protein. AA range:353-402
Storage Stability
-20°C for one year
Concentration
1 mg/ml
MolecularWeight_Da
71027
synonyms
RACGAP1; KIAA1478; MGCRACGAP; Rac GTPase-activating protein 1; Male germ cell RacGap; MgcRacGAP; Protein CYK4 homolg; CYK4; HsCYK-4
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