ABCbiolab
SKU:ABCCS44243
RAB5A Antibody
RAB5A Antibody
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Size
100ul
Clone Number
Aliases
RAB 5 antibody; RAB 5A antibody; RAB5A antibody; RAB5A member RAS oncogene family antibody; RAB5A_HUMAN antibody; RAS associated protein RAB5A antibody; Ras related protein Rab 5A antibody; Ras-related protein Rab-5A antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
P20339
Immunogen
Recombinant Human Ras-related protein Rab-5A protein (1-215AA)
Raised in
Rabbit
Species Reactivity
Human, Mouse
Tested Applications
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200
Background
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension.
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
RAB5A
Research Areas
Neuroscience; Tags & Cell Markers; Signal transduction
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