RAB3IP Antibody

Size

100ug

Clone Number

Aliases

Gtpat12 antibody; Rab-3A-interacting protein antibody; RAB3A interacting protein antibody; RAB3A interacting protein (rabin3) antibody; RAB3A interacting protein antibody; RAB3A-interacting protein antibody; RAB3I_HUMAN antibody; Rab3ip antibody; Rabin 3 antibody; Rabin-3 antibody; RABIN3 antibody; RABIN3; rat; homolog of antibody; Rabin8 antibody; SSX2 interacting protein antibody; SSX2 interacting protein antibody; SSX2-interacting protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96QF0

Immunogen

Recombinant Human Rab-3A-interacting protein (1-132AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RAB3IP

Research Areas

Cell biology; Signal transduction