RAB12 Antibody

Size

100ug

Clone Number

Aliases

Putative Ras related protein Rab 12 antibody; RAB12 antibody; RAB12; member RAS oncogene family antibody; RAB12_HUMAN antibody; Ras-related protein Rab-12 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6IQ22

Immunogen

Recombinant Human Ras-related protein Rab-12 protein (98-241AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200

Background

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

RAB12

Research Areas

Signal transduction