SOX7 Antibody

SOX7 belongs to SOX gene family and member proteins are transcription factors with critical roles in the regulation of diverse developmental processes. In cotransfected 293 cells, SOX7 reduced Wnt/beta-catenin stimulated transcription. SOX7 is a potent activator of FGF3 transcription. It not only plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium but also blocks further differentiation into blood precursors. And it may be required for the survival of both hematopoietic and endothelial precursors during specification.