CYP2U1 Antibody

Cytochrome P450, Family 2, Subfamily U, Polypeptide 1 is a protein that in humans is encoded by the CYP2U1 gene. Members of the P450 enzyme family have roles in the tissue-specific conversion of substrates into locally active hormones, vitamins, and signaling molecules, including arachidonic acid derivatives known as eicosanoids. The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 4.Chuang et al.(2004) stated that CYP2U1 maps to 4q25. Using recombination experiments in Sf9 insect cells, Chuang et al.(2004) found that CYP2U1 metabolized arachidonic acid, docosahexaenoic acid(DHA), and other long chain fatty acids. Chuang et al.(2004) suggested that CYP2U1 may play a role in brain and immune functions.