ALDH1A1 Antibody

Aldehyde dehydrogenase 1 family, member A1, also called ALDH1, RALDH1 or ALDH, is an enzyme that in humans is encoded by the ALDH1A1 gene. And this protein belongs to the aldehyde dehydrogenases family of proteins. The gene is mapped on 9q21.13. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea. It is associated with a low Km for NAD, a high Km for acetaldehyde, and is strongly inactivated by disulfiram. Retinaldehyde is generated by ADH1 from retinol, and its concentration is determined in large part by its subsequent catabolism by ALDH1A1 to retinoic acid.