NMDAR2B Antibody

The N-methyl-D-aspartate receptor 2B is also called GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98% and 96% identical to the sequences of the rat and mouse proteins, respectively. The gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Overexpression of NMDAR2B in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz.