GST pi Antibody (GST3)

Glutathione S-transferases pi, also known as GST pi and GST3, is present in all tissues and cells, with the exception of red cells, in which only erythrocyte GST(GSTe) is observed. The gene has 7 exons and 6 introns contained within approximately 2.8 kilobases. It is mapped to chromosome 11 . Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. GST pi does not contribute in vivo to the formation of glutathione conjugates of acetaminophen but plays a novel and unexpected role in the toxicity of this compound.