PU.1 Polyclonal Antibody

Ab type

Primary antibody

Background

SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. Spi-1 proto-oncogene can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this SPI1.

Reactivity

Human;Mouse;Rat;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human SPI1. AA range:181-230

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

31083

synonyms

SPI1; Transcription factor PU.1; 31 kDa-transforming protein