PTPRH Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth| differentiation| mitotic cycle| and oncogenic transformation. This PTP possesses an extracellular region| a single transmembrane region| and a single intracytoplasmic catalytic domain| and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver| and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines| but not in the corresponding normal tissues. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human PTPRH

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

122650

synonyms

PTPRH