PTPRA Antibody

Size

100ul

Clone Number

Aliases

HEPTP antibody; HLPR antibody; HPTP alpha antibody; HPTPA antibody; HPTPalpha antibody; Leukocyte common antigen related peptide antibody; LRP antibody; Protein tyrosine phosphatase alpha antibody; Protein tyrosine phosphatase receptor type A antibody; Protein tyrosine phosphatase receptor type alpha polypeptide antibody; Protein tyrosine phosphate antibody; Protein-tyrosine phosphatase alpha antibody; PTPA antibody; PTPalpha antibody; PTPase alpha antibody; PTPLCA related phosphatase antibody; Ptpra antibody; PTPRA_HUMAN antibody; PTPRL 2 antibody; PTPRL2 antibody; PTRA antibody; R PTP alpha antibody; R-PTP-alpha antibody; Receptor type tyrosine protein phosphatase alpha antibody; Receptor-type tyrosine-protein phosphatase alpha antibody; RPTPA antibody; Tyrosine phosphatase alpha antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P18433

Immunogen

Recombinant Human Receptor-type tyrosine-protein phosphatase alpha protein (20-142AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PTPRA

Research Areas

Signal transduction