PTPN11 Antibody

Size

100ug

Clone Number

Aliases

BPTP3 antibody; CFC antibody; JMML antibody; METCDS antibody; MGC14433 antibody; NS1 antibody; OTTHUMP00000166107 antibody; OTTHUMP00000166108 antibody; Protein tyrosine phosphatase 2 antibody; Protein tyrosine phosphatase 2C antibody; Protein tyrosine phosphatase non receptor type 11 antibody; Protein-tyrosine phosphatase 1D antibody; Protein-tyrosine phosphatase 2C antibody; PTN11_HUMAN antibody; PTP-1D antibody; PTP-2C antibody; PTP1D antibody; PTP2C antibody; PTPN11 antibody; SAP2 antibody; SH-PTP2 antibody; SH-PTP3 antibody; SH2 domain containing protein tyrosine phosphatase 2 antibody; SHP 2 antibody; SHP-2 antibody; Shp2 antibody; SHPTP2 antibody; SHPTP3 antibody; Syp antibody; Tyrosine-protein phosphatase non-receptor type 11 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q06124

Immunogen

Recombinant Human Tyrosine-protein phosphatase non-receptor type 11 protein (246-520AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PTPN11

Research Areas

Neuroscience; Signal transduction