PSP Polyclonal Antibody

Ab type

Primary antibody

Background

PSPN encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. Persephin signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human PSPN. AA range:101-150

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

16600

synonyms

PSPN; Persephin; PSP