PSMD4 Antibody

Size

100ul

Clone Number

Aliases

26S protease subunit S5a antibody; 26S proteasome non ATPase regulatory subunit 4 antibody; 26S proteasome non-ATPase regulatory subunit 4 antibody; 26S proteasome regulatory subunit rpn10 antibody; 26S proteasome regulatory subunit S5A antibody; AF 1 antibody; AF antibody; AF1 antibody; Angiocidin antibody; Antisecretory factor 1 antibody; ASF antibody; DS5a antibody; MCB 1 antibody; MCB1 antibody; Multiubiquitin chain binding protein antibody; Multiubiquitin chain-binding protein antibody; OTTHUMP00000059963 antibody; Prosome macropain antibody; Proteasome (prosome macropain) 26S subunit non ATPase 4 antibody; Proteasome 19S S5A antibody; Proteasome 26S non ATPase subunit 4 antibody; Proteasome 26S subunit non ATPase 4 antibody; PSMD 4 antibody; Psmd4 antibody; PSMD4_HUMAN antibody; pUB R5 antibody; pUBR5 antibody; Rpn 10 antibody; Rpn10 antibody; RPN10 homolog antibody; S5A antibody; S5a/antisecretory factor protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P55036

Immunogen

Recombinant Human 26S proteasome non-ATPase regulatory subunit 4 protein (161-377AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PSMD4

Research Areas

Cell biology