PSMC5 Antibody

Size

100ug

Clone Number

Aliases

26S protease regulatory subunit 8 antibody; 26S proteasome AAA-ATPase subunit RPT6 antibody; Cim3 antibody; MSUG1 protein antibody; p45 antibody; p45/SUG antibody; Proteasome 26S ATPase subunit 5 antibody; Proteasome 26S subunit ATPase 5 antibody; Proteasome prosome macropain 26S subunit ATPase 5 antibody; Proteasome subunit p45 antibody; PRS8_HUMAN antibody; PSMC5 antibody; Rpt6 antibody; S8 antibody; SUG1 antibody; Tat binding protein homolog 10 antibody; TBP10 antibody; Thyroid hormone receptor interacting protein 1 antibody; Thyroid hormone receptor-interacting protein 1 antibody; Thyroid receptor interactor 1 antibody; TRIP1 antibody; TRIP1(SUG1) antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P62195

Immunogen

Recombinant Human 26S proteasome regulatory subunit 8 protein (253-324AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:500

Background

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PSMC5

Research Areas

Cell biology