PSEN2 Antibody

Size

100ug

Clone Number

Aliases

AD3L antibody; AD3LP antibody; AD4 antibody; AD5 antibody; Alzheimer disease 4 antibody; CMD1V antibody; E5-1 antibody; OTTHUMP00000035671 antibody; OTTHUMP00000035672 antibody; OTTHUMP00000228286 antibody; OTTHUMP00000228288 antibody; Presenilin 2 (Alzheimer disease 4) antibody; Presenilin 2 antibody; Presenilin-2 CTF subunit antibody; PS-2 antibody; PS2 antibody; Psen2 antibody; PSN2_HUMAN antibody; PSNL2 antibody; STM-2 antibody; STM2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P49810

Immunogen

Recombinant Human Presenilin-2 protein (7-77AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PSEN2

Research Areas

Neuroscience; Cancer; Metabolism