Mouse FGF1 Protein

Mouse FGF1, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. It is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. Intracellular Mouse FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signalin.