Protein C Polyclonal Antibody

Ab type

Primary antibody

Background

PROC encodes a vitamin K-dependent plasma glycoprotein. The vitamin K-dependent protein C is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human PROC. AA range:181-230

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

52071

synonyms

PROC; Vitamin K-dependent protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV