PROK1 Antibody

Size

100ug

Clone Number

Aliases

Black mamba toxin related protein antibody; EG VEGF antibody; EG-VEGF antibody; EGVEGF antibody; Endocrine-gland-derived vascular endothelial growth factor antibody; Mambakine antibody; PK1 antibody; PRK1 antibody; PROK1 antibody; PROK1_HUMAN antibody; Prokineticin 1 antibody; Prokineticin-1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P58294

Immunogen

Recombinant Human Prokineticin-1 protein (20-105AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PROK1

Research Areas

Signal transduction