PROC Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency| neonatal purpura fulminans| and recurrent venous thrombosis.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human PROC (light chain| Cleaved-Leu179)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

50710

synonyms

PROC ;light chain; Cleaved-Leu179; Vitamin K-dependent protein C; EC 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide;