Probetacellulin Polyclonal Antibody

Ab type

Primary antibody

Background

BTC encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of betacellulin bind to multiple different EGF receptors. Betacellulin romotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in BTC may be associated with type 2 diabetes in human patients.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from Probetacellulin . at AA range: 60-140

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

19746

synonyms

BTC; Probetacellulin