PRKAB1 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

1300015D22Rik antibody; 5''-AMP-activated protein kinase subunit beta-1 antibody; 5'-AMP-activated protein kinase beta-1 subunit antibody; AAKB1_HUMAN antibody; AMP-activated protein kinase beta subunit antibody; AMP-ACTIVATED PROTEIN KINASE; NONCATALYTIC; BETA-1 antibody; AMP-activated; noncatalytic; beta-1 antibody; AMPK antibody; AMPK beta 1 chain antibody; AMPK subunit beta-1 antibody; AMPK-BETA-1 antibody; AMPKb antibody; AU021155 antibody; E430008F22 antibody; HAMPKb antibody; MGC17785 antibody; PRKAB1 antibody; Protein kinase AMP activated non catalytic subunit beta 1 antibody; protein kinase; AMP-activated; beta 1 non-catalytic subunit antibody; protein kinase; AMP-activated; noncatalytic; beta-1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y478

Immunogen

Recombinant Human 5\'-AMP-activated protein kinase subunit beta-1 protein (1-270AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PRKAB1

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction