PRICKLE3 Antibody

Size

100ul

Clone Number

Aliases

PRICKLE3 antibody; LMO6Prickle planar cell polarity protein 3 antibody; LIM domain only protein 6 antibody; LMO-6 antibody; Prickle-like protein 3 antibody; Pk3 antibody; Triple LIM domain protein 6 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O43900

Immunogen

Peptide sequence from Human Prickle-like protein 3 protein (9-24AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules, PRICKLE3 being part of the core module (By similarity). Distinct complexes of the core module segregate to opposite sides of the cell, where they interact with the opposite complex in the neighboring cell at or near the adherents junctions (By similarity). Involved in the organization of the basal body (By similarity). Involved in cilia growth and positioning (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PRICKLE3

Research Areas

Cell biology