PREX1 Antibody

Size

100ug

Clone Number

Aliases

4 antibody; 5)-dependent Rac exchanger 1 antibody; KIAA1415 antibody; OTTHUMP00000031228 antibody; P REX1 antibody; P Rex1 protein like antibody; P-Rex1 antibody; Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchange factor 1 antibody; Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 antibody; Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 protein antibody; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein antibody; Prex1 antibody; PREX1_HUMAN antibody; PtdIns(3 antibody; PtdIns(3,4,5) dependent Rac exchanger 1 antibody; SET domain containing 6 antibody; Setd6 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8TCU6

Immunogen

Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (1-44AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PREX1

Research Areas

Cell biology; Signal transduction