Prealbumin Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes transthyretin| one of the three prealbumins including alpha-1-antitrypsin| transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid| and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition| affecting predominantly peripheral nerve and/or the heart| and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy| euthyroid hyperthyroxinaemia| amyloidotic vitreous opacities| cardiomyopathy| oculoleptomeningeal amyloidosis| meningocerebrovascular amyloidosis| carpal tunnel syndrome| etc.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human Prealbumin

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

16170

synonyms

Prealbumin; Transthyretin; ATTR; Prealbumin; TBPA