PRDM5 Antibody

Size

100ug

Clone Number

Aliases

BCS2 antibody; PFM 2 antibody; PFM2 antibody; PR domain containing 5 antibody; PR domain containing protein 5 antibody; PR domain zinc finger protein 5 antibody; PR domain-containing protein 5 antibody; PRDM 5 antibody; PRDM5 antibody; PRDM5 protein antibody; PRDM5_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NQX1

Immunogen

Recombinant Human PR domain zinc finger protein 5 protein (29-111AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PRDM5

Research Areas

Epigenetics and Nuclear Signaling