ABCbiolab
SKU:ABCB09651
PRDM2 Rabbit Polyclonal Antibody
PRDM2 Rabbit Polyclonal Antibody
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Ab type
Primary antibody
Background
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein| estrogen receptor| and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized| it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma| (2) act as a transcriptional activator of the heme-oxygenase-1 gene| and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human, Rat
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
Synthesized peptide derived from human PRDM2
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
188980
synonyms
PRDM2
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