PRDM16 Antibody

Size

100ug

Clone Number

Aliases

CMD1LL antibody; KIAA1675 antibody; LVNC8 antibody; MDS1/EVI1 like gene 1 antibody; MDS1/EVI1-like gene 1 antibody; MEL1 antibody; PFM 13 antibody; PFM13 antibody; PR domain containing 16 antibody; PR domain containing protein 16 antibody; PR domain zinc finger protein 16 antibody; PR domain-containing protein 16 antibody; PRD16_HUMAN antibody; Prdm16 antibody; Transcription factor MEL 1 antibody; Transcription factor MEL1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HAZ2

Immunogen

Recombinant Human PR domain zinc finger protein 16 protein (448-683AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

PRDM16

Research Areas

Epigenetics and Nuclear Signaling