ABCbiolab
SKU:ABCB07047
PR(Phospho Ser400) Polyclonal Antibody
PR(Phospho Ser400) Polyclonal Antibody
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Ab type
Primary antibody
Background
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone| which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants| both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human Progesterone Receptor around the phosphorylation site of Ser400. AA range:371-420
Storage Stability
-20°C for 1 year
Concentration
1 mg/ml
MolecularWeight_Da
98981
synonyms
Progesterone receptor; PGR; NR3C3; Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3
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